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Image Search Results
Journal: Cytotherapy
Article Title: Characterizing human mesenchymal stromal cells’ immune-modulatory potency using targeted lipidomic profiling of sphingolipids
doi: 10.1016/j.jcyt.2021.12.009
Figure Lengend Snippet: Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) PCA of high and low IDO unstimulated (Unstim) MSC groups. (D) PCA variable plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Article Snippet: Graphical illustrations of
Techniques: MANN-WHITNEY